Rescue of the Red-Eyed Tree Frogs is the first episode in the first season of Go, Diego, Go!
Diego and Baby Jaguar must rescue a pair of red-eyed tree frogs before they slide down a waterfall.
- Sloths (debut)
- This is the first episode for the series introducing almost every main character.
- Baby Jaguar is the one who starts off this episode instead of Diego.
- The viewers get an inside view of what the Animal Rescue Center looks like.
- This series is a spin-off of Dora the Explorer. Diego has almost everything that Dora has. He can speak Spanish and speaks to the viewers.
- This episode premiered at 8:00pm on Nickelodeon. That same day, Nick Jr. did a Dora the Explorer marathon to promote the series premiere of Go, Diego, Go! with the last episode on the schedule being the premiere of Dora & Diego to the Rescue at 1:30pm.
- This is the first episode Baby Jaguar and Diego zipline after Alicia says "Go, Diego, Go!".
- After Baby Jaguar finds Diego, the plants on the bottom right side disappear.